Kinetics of Thiazole Formation Using α-Halo Ketones and Thioamides
نویسندگان
چکیده
The current approach involves the kinetic investigation of Thiobenzamide (TB) and cyclohexanone thiosemicarbazone (CTSC) in solution with 3-chloroacetylacetone(3-CAA). study revealed a second-order rate constant respect to both reactants, thioamide an α-halo carbonyl compound. energy activation (Ea) was found be Ea 48.8176 kJ/mol/K for thiobenzamide 33.08692157 Cyclohexanone thiosemicarbazone. salt effect showed formation ionic species during reaction. reactions were studied changes dielectric using solvent systems like water-ethanol water-isopropanol.
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ژورنال
عنوان ژورنال: Oriental journal of chemistry
سال: 2022
ISSN: ['0970-020X', '2231-5039']
DOI: https://doi.org/10.13005/ojc/380427